Clinical research trials reveal new discoveries, uncover future treatments, and provide answers to our questions. This section of our resource center presents cancer-related trials on various types of cancer from medical institutions around the world.
Johns Hopkins Medicine researchers have found that a shortage of specific tiny molecules that silence certain genes are linked to the development and growth of …
Any therapy that aims at eradicating a cancerous growth will have at its core a cell death-inducing component. Here we argue that paediatric oncology presents …
With continued improvements in survival following childhood cancer, the long-term health consequences of cancer treatments are receiving greater focus. Diabetes is emerging as a potential late effect of cancer therapy; however, the magnitude …
Chemotherapy for childhood acute lymphoblastic leukemia (ALL) can cause late-appearing side effects in survivors that affect multiple organs, including the heart and brain. However, the complex ALL …
The prognosis of patients with recurrent World Health Organization (WHO) grade IV malignant glioma is dismal, and there is currently no effective therapy. We conducted …
Tissue-resident memory CD8+ T (TRM) cells are found at common sites of pathogen exposure, where they elicit rapid and robust protective immune responses1,2. However, the molecular …
FDA approves test to detect mutations in 324 genes, two genomic signatures. Second to be approved with proposed coverage under FDA/CMS Parallel Review Program. The …
Glioblastoma (GBM) is a devastating malignancy with few therapeutic options. We identify PRMT5 in an in vivo GBM shRNA screen and show that PRMT5 knockdown or inhibition potently …
ABSTRACT: Early clinical studies showed that high-dose vitamin C, given by intravenous and oral routes, may improve symptoms and prolong life in patients with terminal …
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