Intracellular Signaling Mechanisms in Thyroid Cancer
Jul 18 2016Thyroid cancer is the most common malignancy of the endocrine system, the papillary variant accounts for 80-90% of all diagnosed cases. In the development of …
RESOURCES
Clinical Trials
Clinical research trials reveal new discoveries, uncover future treatments, and provide answers to our questions. This section of our resource center presents cancer-related trials on various types of cancer from medical institutions around the world.
ALL LATEST ENTRIES
Reactive Astrocytes Potentiate Tumor Aggressiveness in a Murine Glioma Resection and Recurrence Model
Jul 6 2016Surgical resection is a universal component of glioma therapy. Little is known about the postoperative microenvironment due to limited preclinical models. Thus, we sought to …
Fatty Acid Oxidation is Required For The Respiration and Proliferation of Malignant Glioma
Jul 5 2016Glioma is the most common form of primary malignant brain tumor in adults, with approximately 4 cases per 100 000 people each year. Gliomas, like …
Blood-Brain Barrier Permeable Gold Nanoparticles: An Efficient Delivery Platform for Enhanced Malignant Glioma Therapy and Imaging
May 9 2016The blood-brain barrier (BBB) remains a formidable obstacle in medicine, preventing efficient penetration of chemotherapeutic and diagnostic agents to malignant gliomas. Here, we demonstrate that …
Arming NK Cells with Enhanced Antitumor Activity
May 5 2016Natural killer (NK) cells hold great promise for adoptive cancer immunotherapy. The antitumor activity of NK cells can be enhanced by the transgene driven expression …
Improving Patient Outcomes to Targeted Therapies in Melanoma
May 4 2016The arrival of targeted therapies has led to significant improvements in clinical outcomes for BRAFV600 mutated advanced melanoma patients over the past five years. In …
Divergent Clonal Selection Dominates Medulloblastoma at Recurrence
Apr 18 2016The development of targeted anti-cancer therapies through the study of cancer genomes is intended to increase survival rates and decrease treatment-related toxicity. In this study, …
TCR Sequencing Can Identify and Track Glioma-infiltrating T Cells After DC Vaccination
Apr 7 2016While immunotherapeutic strategies are emerging as adjunctive treatments for cancer, sensitive methods of monitoring the immune response after treatment remain to be established. We used …
Apoptosis-inducing Effects of Melissa Officinalis L. Essential Oil in Glioblastoma Multiforme Cells
Mar 22 2016Current therapies for glioblastoma multiforme (GBM) are not effective. This study investigated the activity of the M. officinalis essential oil (EO) and its major component …
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