The Relationship Between Breast Cancer and Thyroid Disease
Aug 15 2016The relationship between thyroid dysfunction and breast cancer (BC) is debated. To clarify this controversial issue, a prospective study on thyroid function in BC was …
RESOURCES
Clinical Trials
Clinical research trials reveal new discoveries, uncover future treatments, and provide answers to our questions. This section of our resource center presents cancer-related trials on various types of cancer from medical institutions around the world.
ALL LATEST ENTRIES
Novel Drugs That Target the Metabolic Reprogramming in Renal Cell Cancer
Jul 18 2016Molecular profiling studies of tumor tissue from patients with clear cell renal cell cancer (ccRCC) have revealed extensive metabolic reprogramming in this disease. Associations were …
Intracellular Signaling Mechanisms in Thyroid Cancer
Jul 18 2016Thyroid cancer is the most common malignancy of the endocrine system, the papillary variant accounts for 80-90% of all diagnosed cases. In the development of …
Reactive Astrocytes Potentiate Tumor Aggressiveness in a Murine Glioma Resection and Recurrence Model
Jul 6 2016Surgical resection is a universal component of glioma therapy. Little is known about the postoperative microenvironment due to limited preclinical models. Thus, we sought to …
Fatty Acid Oxidation is Required For The Respiration and Proliferation of Malignant Glioma
Jul 5 2016Glioma is the most common form of primary malignant brain tumor in adults, with approximately 4 cases per 100 000 people each year. Gliomas, like …
Blood-Brain Barrier Permeable Gold Nanoparticles: An Efficient Delivery Platform for Enhanced Malignant Glioma Therapy and Imaging
May 9 2016The blood-brain barrier (BBB) remains a formidable obstacle in medicine, preventing efficient penetration of chemotherapeutic and diagnostic agents to malignant gliomas. Here, we demonstrate that …
Arming NK Cells with Enhanced Antitumor Activity
May 5 2016Natural killer (NK) cells hold great promise for adoptive cancer immunotherapy. The antitumor activity of NK cells can be enhanced by the transgene driven expression …
Improving Patient Outcomes to Targeted Therapies in Melanoma
May 4 2016The arrival of targeted therapies has led to significant improvements in clinical outcomes for BRAFV600 mutated advanced melanoma patients over the past five years. In …
Divergent Clonal Selection Dominates Medulloblastoma at Recurrence
Apr 18 2016The development of targeted anti-cancer therapies through the study of cancer genomes is intended to increase survival rates and decrease treatment-related toxicity. In this study, …
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