January 19, 2016 -

Chondroblastoma is a rare, benign bone tumor comprised of cells that produce cartilage, known as chondroblasts. It is usually found in the epiphysis (ends) of long bones, usually of the lower extremity. The most common sites are the distal femur (thigh bone), proximal humerus (upper arm bone) and proximal tibia (shin bone). Sometimes it is found in the iliac crest or acetabelum (socket) of the hip.

The tumor appears more often in males than females and tends to occur during the second decade of life. Most of the time, it occurs before skeletal maturity (when full growth potential of the bones is achieved).

The tumor is considered benign, yet it may not always behave that way. Chondroblastoma is one of the few benign bone tumors that have the potential to metastasize (spread) to the lungs.

Chondroblastoma occurs when a single chondroblast (cell that produces cartilage) abnormally divides out of control. Why this occurs is unknown. There is apparently no association between chondroblastoma and repeated trauma.

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