Synovial Sarcoma

January 26, 2016 -

Synovial sarcoma is a malignant tumor of the soft tissues, usually around joints. Under the microscope the tumor resembles synovial tissue (the lining tissue of joints). Synovial tissue is found around the tendons (bands of fiber that connect muscle to bone), and can form bursa (fluid filled cushioning pouches or sacs found in spaces between tendons, ligaments and bones) found in the area of joints.

This condition tends to occur in adolescents and young adults and affects more males than females. The most common location of origin is the thigh near the knee, but synovial sarcoma can also occur near other joints, mainly in the arms and legs. Despite its name, it seldom arises within a joint.

Synovial sarcoma can spread (metastasize) to other areas of the body, particularly to involve regional lymph nodes. Metastasis to distant body tissues occurs in about half of all cases, usually months to years after the initial diagnosis is made, although they are at times present at diagnosis.

Synovial sarcoma is a rare tumor. It is one of many types of cancer classified as a soft tissue sarcoma, cancer that originates in soft tissue which includes fat, muscles, tendons, nerves, synovial tissue, blood vessels and other fibrous tissue. As a group, soft tissue sarcomas account for less than 1 percent of all new cancer cases each year. In the United States, approximately 900 children and adolescents are diagnosed with soft tissue sarcomas each year.

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