World First: Blood-Brain Barrier Opened Non-Invasively to Deliver Chemotherapy

January 11, 2016 -

History is being made! Sunnybrook scientists are using focused ultrasound to non-ivasively breach the blood-brain barrier and more effectively deliver chemotherapy into the brain tumor of a patient. Did you know that each person has a protective barrier in their brain? This normally restricts the passage of substances from the bloodstream into the bran to protect it from toxic chemicals.

“The blood-brain barrier (BBB) has been a persistent obstacle to delivering valuable therapies to treat disease such as tumours,” says Dr. Todd Mainprize, principal investigator of the study and Neurosurgeon in the Hurvitz Brain Sciences Program at Sunnybrook Health Sciences Centre.

“We are encouraged that we were able to temporarily open this barrier in a patient to deliver chemotherapy directly to the brain tumour.”

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